Yellow fever presents as a dangerous viral disease transmitted through the bite of infected mosquitoes. Signs and Symptoms can range from mild to severe, including elevated body heat, headache, muscle aches, nausea, vomiting, and jaundice. In critical cases, yellow fever can lead to liver failure, kidney damage, bleeding disorders, and even death.

Famotidine is a widely utilized medication belonging to the category of histamine H2 receptor antagonists. Its primary function is to suppress gastric acid secretion, thereby alleviating symptoms associated with various gastrointestinal disorders. The mechanism of action of famotidine involves hampering the binding of histamine to its H2 receptors